【文献解读】NATURE COMMUNICATIONS：Cleavage and nuclear localization of the rice XA21 immune receptor

rice XA21 (Xanthomonas resistance 21)

结果：

总结：XA21在其识别的effector介导下，C端的kinase会被切割下来进入细胞核，和WRKY62互作，调节水稻的抗病性。有意思的是，XA21的核定位是其介导植物免疫所必需的的，如果在XA21上连接一个NES，使蛋白从核中输出，XA21就无法增强植物的抗病性了。

日积月累：

1.Plants and animals carry specificreceptors that recognize invading pathogens and respond

by activating an immune response.

2. Plants and animals perceive conservedmicrobial signatures via plasma membrane and cytoplasmically localizedreceptors.

nuclear export signal (NES)

transmembrane (TM) : adj. 横跨膜的

juxtamembrane (JM) : 近膜区

perinuclear: adj. 细胞核周围的

days afer inoculation (DAI)

colony-forming units (c.f.u.) per leaf (cfu/ leaf)

proteolytic: adj. [生化] 蛋白水解的；解蛋白的n. 解朊作用